Few days after losing 4-2 to Leicester City in the English Premier League, Manchester United will host Atalanta on match day three of the UEFA Champions League.
This is not the best of moments for the Red Devils having lost their last two matches and taken only a point in their last three in the Premier League.
After losing their first group match to Young Boys of Switzerland, United came from behind to beat Villarreal.
Atalanta, who are sixth in the serie A, are leading the group with four points.
United will be missing the services of the France duo of Raphael Varane and Anthony Martial due to injury.
However, the squad has been bolstered with the return of Edinson Cavani and Fred, who both missed the defeat to the Foxes.
Right back, Aaron Wan-Bissaka is also available after serving a match ban.
Defending champions, Chelsea welcome Malmo FF of Sweden. The Blues are second in the group with three points after losing their last match by a lone goal to Juventus.
In other fixtures for tonight, Zenit St Petersburg will host Juventus while Lille welcome Sevilla.
Young Boys will take on Villarreal as Benfica tread tackles with Bayern Munich.
RB Salzburg will lurk horns with Wolfsburg as Barcelona welcome Dynamo Kyiv to the Nou Camp.