BBC-It is the first time in 36 years Tottenham will face German giants Bayern Munich in a competitive fixture and the two are tipped to fight it out for the top spot in Group B.
While Spurs drew their opening game with Olympiakos in Greece, group leaders Bayern beat Serb champions Red Star Belgrade 3-0 in a dominant display in Munich.
Bayern remain unbeaten in their six league games this season too, while last year’s Champions League runners-up Tottenham have won just three of their Premier League matches and are struggling for form.
The two teams met in pre-season and it was Spurs who came out on top – winning a penalty shootout after drawing 2-2 in the Audi Cup final.
Bayern may be a team in transition following the departures of wingers Arjen Robben and Franck Ribery, as well as defender Mats Hummels, but they have brought in the talents of Philippe Coutinho, Ivan Perisic and Lucas Hernandez – all of whom are likely to play on Tuesday.
Ex-Liverpool midfielder Coutinho was linked with a move back to the Premier League this summer and he has made an impression in Germany, contributing to four goals in his first three starts.
He scored twice against Tottenham while playing at Liverpool and the on-loan Barcelona star is now part of a Bayern squad bidding for a sixth European title.
Other fixtures for tonight will see Lokomotiv Moscow take on Atletico Madrid as Red Star host Olympiakos.
Italian side Atalanta will confront Shakhtar Donetsk while Bayer Leverkusen will travel to Turin to face Cristiano Ronaldo’s Juventus.
English champions, Manchester City will lurk horns with Dinamo Zagreb as Galatasaray host PSG.
Real Madrid will welcome Club Brugge to the Santiago Benabau.