Victor Osimhen and his Napoli teammates gave Liverpool manager Jurgen Klopp a lot to think about with an emphatic 4-1 victory. The scoreline would have been worse with a lot of chances not converted including a first half penalty miss by Victor Osimhen.
Liverpool are yet to get into their usual stride this season and fans are fast losing patience.
In other matches, Ajax hammered Rangers 4-0 as Atletico Madrid pipped Porto 2-1.
Club Bruges defeated Bayer Leverkusen 1-0 as Barcelona crushed Vicktoria Plzen 5-1.
Bayern Munich left Italy with all three points after defeating Inter Milan 2-0.
Former Everton striker Richarlison scored a brace to give Tottenham Hotspur a 2-0 victory over Marseille.